Patients with advanced pancreatic cancer can have the following symptoms: first, abdominal pain, patients can have pain in the upper abdomen or left upper abdomen, sometimes the pain is intolerable, and it is often considered that the tumor has invaded the retroperitoneal plexus. Second, mass, in the upper abdomen can be touched hard mass, poor mobility, pressure and pain. Third, gastrointestinal symptoms, which can be manifested as nausea, vomiting, abdominal distension, poor gas and defecation, and sometimes it is difficult to pass gas and defecation. Fourth, jaundice, when the tumor invades the biliary tract, there can be yellowing of skin and yellowing of eyes, combined with deepening of urine color, whitening of stools, itching of skin and other symptoms. Fifthly, patients may have the symptoms of progressive wasting and anemia. Sixthly, patients may have obvious abdominal distension, and sometimes the abdomen will be positive for mobile turbid sound, which is often considered as hypoproteinemia or carcinomatous ascites.