The soles of the feet can be particularly yellow may be a physiological phenomenon, may also be hypercarotenemia, hepatocellular jaundice and cholecystitis and other causes. 1. Physiological phenomenon: Physiologically, the soles of human feet form a stratum corneum. When the epidermis, which consists of many keratin-forming cells, grows and develops with the body, the soles of the feet of some people with a thicker stratum corneum will turn yellow. 2. Hypercarotenemia: Yellowing of the skin due to high carotenoid levels in the blood, which can affect the whole body, including the soles of the feet. 3. Hepatocellular jaundice: Hepatocellular damage caused by viral hepatitis, cirrhosis of the liver and toxic hepatitis can be manifested as yellowing of the skin and mucous membranes, accompanied by itching of the skin. 4. Cholecystitis: If the patient suffers from cholecystitis, it will lead to poor excretion of bile, which will lead to the symptoms of yellowing of the soles of the feet. There may be other reasons for the yellowing of the soles of the feet, patients need to go to the hospital in time for blood tests to confirm the diagnosis, and please ask a professional doctor for proper treatment.