Sleeping pills have a very small effect on sexual function, such as the commonly used diazepam and Librium, which have to be used in very large doses before they are likely to affect libido and erection. In fact, many other drugs will have different degrees of impact on sexual function, such as anti-hypertensive drugs, methyldopa, colestipol, propranolol, as well as guanethidine, hydralazine, thiazide diuretics, rifampicin, etc., will have different degrees of impact on libido, erection and ejaculation. Among the antipsychotics, amitriptyline, promethazine, methotrexate, and barbiturates can also affect libido, erection, and ejaculation to varying degrees. Anti-estrogenic drugs, such as corticosteroids, spironolactone, cimetidine, and fluoroacetamide, can also have an effect on libido and erection. There are also antihistamines such as chlorpropamide and diphenylhydantoin that can affect libido. Sleeping pills are safe for most people to use and there is no need to worry that they will have much effect on sexual function.