Glomerular filtration rate of 30ml/min, suggesting that renal function has been seriously impaired, may be acute kidney injury, or chronic kidney disease, the cause of different treatments are different, should be timely consultation. There are general treatment and drug treatment. In case of acute kidney injury, resulting in decreased glomerular filtration rate, water and electrolyte balance should be actively maintained, primary disease should be actively treated, and infection should be prevented and controlled. Plasma replacement, glucocorticoid shock and glucocorticoid combined with immunosuppressant, such as glucocorticoid methylprednisolone combined with cyclophosphamide treatment, are often needed. In case of chronic kidney disease, the treatment needs to be directed at the primary disease, such as chronic glomerulonephritis caused by chronic renal failure needs to actively control blood pressure and reduce proteinuria. Chronic renal failure caused by diabetic nephropathy requires active control of blood pressure, blood glucose, blood lipids, and at the same time, for edema, you can apply diuretics with tabs, thiazide diuretics, such as hydrochlorothiazide, furosemide for diuretic and edema treatment. The glomerular filtration rate of 30ml/min, should be timely hospital consultation, under the guidance of the doctor active treatment, so as not to delay the condition.