Double-positive novel coronavirus may refer to both positive nucleic acid and antibody tests or positive double antibody tests. 1. Positive nucleic acid and antibody tests: If the nucleic acid test for novel coronavirus is positive and the antibody test for novel coronavirus is positive, the diagnosis of novel coronavirus infection can usually be confirmed. 2. Positive double antibody test: If both IgG and IgM antibodies are positive for the novel coronavirus, the diagnosis of novel coronavirus infection can also be confirmed. It should be noted that a positive antibody and nucleic acid test, or a positive IgG antibody and IgM antibody for the novel coronavirus, are both indicative of novel coronavirus infection, and should be treated as soon as possible in conjunction with quarantine.