Amebic liver abscess is the most common complication of intestinal amebiasis, occurring mostly within 1 to 3 months after the onset of amebic dysentery. The contents of the abscess are tan and jam-like, consisting of a mixture of liquefied necrotic material and stale blood. The inflammatory response of amoebic liver abscesses is not pronounced, but they are still customarily referred to as abscesses. The wall of the abscess is accompanied by connective tissue, blood vessels, and bile ducts in the confluent area that have not yet completely liquefied and necrotic, giving it a ragged flocculent appearance. Microscopically, the abscess cavity is filled with liquefied necrotic reddish structureless material. Clinically, the severity of amebic liver abscess symptoms is related to the location and size of the abscess and whether it is accompanied by infection. It often presents with prolonged irregular fever with right upper abdominal pain and hepatomegaly and tenderness, and generalized wasting. If amebic liver abscess is not treated promptly, the abscess may continue to expand and penetrate into the surrounding tissues, causing lesions in the corresponding areas. When amoebic liver abscess is diagnosed, standardized treatment should be carried out under the guidance of a doctor.