Red prickly heat on the skin in the second stage of membranous nephropathy can be treated with general therapy, Denuded ointment and other medications. It is recommended to consult a doctor in time for symptomatic treatment. 1. General treatment: It can reduce the itchiness by improving the environment, ventilating more to dissipate heat, and changing clothes frequently. It is recommended to avoid spicy and stimulating food, to light, easy to digest food, eat more fresh fruits and vegetables. 2. medication: itchy skin can be appropriate local topical ointment treatment, such as Dinaid ointment, 1% of the mint glycerite lotion. If the symptoms are more obvious, can be taken orally anti-allergic drugs, such as loratadine or cetirizine. The above medications should be used in accordance with the doctor’s prescription and should not be used without authorization. Membranous nephropathy patients with any discomfort is recommended to regular hospitals, under the guidance of professional doctors, standardized treatment.