Heterotopic calcification is also known as heterotopic ossification. Ectopic ossification is most commonly seen in joint replacements, spinal cord injuries, traumatic craniosynostosis, blast injuries, elbow and acetabular fractures, and thermal injuries. Radiation and certain non-steroidal anti-inflammatory drugs are important ways to prevent heterotopic ossification. Carefully planned surgical resection can improve patient prognosis, regardless of joint involvement or initial cause of injury. Future therapeutic strategies are focused on targeted inhibition of local factors and signaling pathways that catalyze heterotopic osteogenesis. Patients with ectopic calcification should have a diet with high protein content, regular checkups are still necessary, as well as with herbal regimens to find a qualified TCM practitioner who can prescribe the right herbs after identification. Patients suffering from ectopic calcification often precipitate calcium ions from the skeletal system, often leading to the occurrence of osteoporosis, so exercise should pay attention to the strength, not too much labor.