The root cause of gout is not the liver. Gout is a disease caused by high blood uric acid level in the body, leading to the deposition of urate in the joints, resulting in damage to the joints and surrounding tissues, and its etiology and pathogenesis are still unclear, gout is a metabolic disease caused by a combination of factors. Gout is a metabolic disease caused by a combination of factors. Gout is mainly caused by internal purine metabolism disorders, uric acid excretion disorders and heredity, and there is no direct connection with the liver, so the root cause of gout is not the liver. Gout can cause arthritis, gout stones, joint deformities, gouty nephropathy and other manifestations. Therefore, it is recommended that patients with gout should go to the hospital in time, under the guidance of the doctor to standardize the diagnosis and treatment, and regular follow-up.