There are two main reasons for the testicles appearing sometimes big and sometimes small: the first one is caused by inflammation of the testicles and epididymis, which is an inflammatory reaction caused by bacteria and other pathogenic microorganisms infecting the testicles and epididymis through the reproductive tract, and at the same time, painful symptoms of the testicles and epididymis can appear, and a clear diagnosis can be made through ultrasound examination. The main use of anti-inflammatory drugs, such as levofloxacin tablets, cefuroxime tablets continued oral 1-2 weeks, the symptoms can be relieved. In the second case, inguinal hernia may cause such performance, which is caused by the weakness of the abdominal wall, resulting in the descent of the abdominal contents into the scrotum through the inguinal canal, and the diagnosis can be confirmed by ultrasound examination. If the diagnosis of inguinal hernia is confirmed, surgery is required to achieve a complete cure.