Soft tissue infection with skin necrosis usually requires surgical debridement, anti-infective drug treatment and skin grafting surgery to relieve symptoms, control the development of the disease and prevent complications as soon as possible. 1. Surgical debridement: After the occurrence of soft tissue infection and skin necrosis, it is usually necessary to surgically remove the necrotic skin tissue as soon as possible to prevent the spread of infection and aggravation of the phenomenon. 2. Anti-infective drug treatment: soft tissue infection skin necrosis is mainly related to bacterial infection invading local soft tissue and skin, etc. After surgical debridement, anti-infective drugs need to be applied according to the results of drug sensitivity, such as vancomycin or cephradine, etc., in order to better control the infection and promote healing. 3. Skin implantation surgery: due to the phenomenon of skin necrosis, which will lead to local skin loss after debridement, so in the case of local wound cleaning, infection control is better, large areas of skin loss need to be treated with skin implantation surgery. In the process of treatment and recovery, pay attention to dietary regulation, eat more protein and vitamin-rich food, do not smoke and drink, eat less spicy stimulating food, so as not to affect the recovery.