The saturation and concentration of uric acid in the body at 37°C is about 420 μmol/L (7 mg/dl), above which hyperuricemia is defined as hyperuricemia. Clinically, it is divided into primary hyperuricemia and secondary hyperuricemia, and long-term hyperuricemia may lead to gout, so its treatment includes the following aspects: primary hyperuricemia and gout treatment mainly includes the following aspects: 1. general treatment: control the total calorie of diet; limit the consumption of alcohol and high purine food; drink a lot of water to increase the excretion of uric acid; carefully use drugs that inhibit uric acid excretion Drugs that inhibit uric acid excretion, such as thiazide diuretics, etc.; avoid triggering factors and actively treat related diseases. 2. Treatment of hyperuricemia: The aim is to maintain normal uric acid level. Mainly include: uric acid excreting drugs such as benzbromarone, drugs that inhibit uric acid production such as allopurinol, alkaline drugs such as sodium bicarbonate, new uric acid lowering drugs such as selective uric acid reabsorption inhibitors. 3.Treatment of acute gouty arthritis period: Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early. 4. Treatment of intermittent and chronic gout attacks: For patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones, uric acid-lowering therapy should be performed. Treatment principles for secondary hyperuricemia: actively treat the primary disease; try to avoid or reduce the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control acute gouty arthritis attacks as soon as possible. In addition, hyperuricemia and gout are often associated with metabolic syndrome, so comprehensive treatment such as hypotension, lipid reduction, weight loss and improvement of insulin resistance should be actively carried out. Therefore, the treatment of uric acid lowering should be individualized according to the cause and condition of the patient in order to achieve the best treatment effect.