A general glutathione value of 69 U/L is not serious. At this point, the degree of elevated glutathione is not more than twice the normal value, the damage to the liver cells may not be severe, and the patient may not even have clinical symptoms. There are even some cases where the cause of an ALT value of 69 U/L is physiological, such as having eaten a large amount of high-fat food, consumed alcohol or taken certain medications prior to the liver function test, etc. For patients with obvious triggers, a review at a later date may also be considered. It is possible that a glutathione value of 69 U/L is the result of a disease, and whether it is serious or not depends mainly on the nature of the specific disease. In the case of elevated GTA due to malignant tumors such as primary liver cancer, even if the value is only mildly elevated, it can have a significant impact on the survival of the patient, which is more serious. Patients with severe hepatitis will show significant elevation of GTA in the early stage, but as the disease progresses, the value of GTA may decrease instead, the value of bilirubin will show progressive increase, and the separation of bile enzymes will indicate the seriousness of the disease. Therefore, the severity of the disease cannot be judged clinically on the basis of the value of GTA alone, but mainly as a sensitive indicator of liver cell damage. The severity of the disease needs to be combined with clinical symptoms, signs, and relevant auxiliary examination indicators.