Hemoglobin is a kind of pigment protein, which mainly exists in the red blood cells of human body. Hemoglobin has important physiological functions, it can play the function of transporting oxygen and carbon dioxide, but the synthesis process of hemoglobin is very complex, needing a variety of raw materials, of which the basic raw materials for the synthesis of hemoglobin include iron, folic acid, vitamin B12, and proteins, and the lack of any one of these hematopoietic raw materials will cause anemia. In the clinic, if iron deficiency, red blood cells can not use iron to synthesize hemoglobin normally, the patient will appear iron deficiency anemia symptoms, manifested as pale, dizziness, fatigue. By the same token, if folic acid and vitamin B12 are deficient, it will cause megaloblastic anemia, and the patient, in addition to the symptoms of anemia, will also have obvious symptoms of peripheral neuritis such as loss of appetite and numbness of the limbs. If protein deficiency, also easy to cause anemia. So the basic raw materials for synthesizing hemoglobin are iron, folic acid, vitamin B12 and protein.