Cranial defects are extremely harmful to human body, and if repair surgery is not performed in time, it may lead to cranial dizziness, headache, and other manifestations, and even irritability, fear of noise, and psychological shadow. Therefore, once the skull is damaged, skull repair surgery should be done as soon as conditions allow. Cranial repair surgery is a routine surgery of cerebral neurosurgery, the technology is very mature and clinical success cases abound, and the operation period is usually one to two hours. It is worthwhile for patients to consider the choice of repair materials. Traditional titanium mesh materials are prone to large postoperative hot and cold reactions, and with external temperature stimulation, patients are subject to chronic symptoms such as headaches, and postoperative infections are more common. So much so that most patients will undergo secondary surgery. PEEK is a newly developed polymeric biomaterial that has been used for a shorter period of time than titanium mesh, but is many times more effective than titanium mesh in clinical practice. The PEEK material, which is highly restorative of the physiological structure of the skull, is popular with patients because it is comparable to autologous cranial bone in terms of tissue description, hardness, stability, and thermal insulation.