Niu Huang Xie Tu Pill and Niu Huang Shang Qing Pill, these two drugs are relatively similar in terms of efficacy and main treatment, both can clear heat and detoxify (remove heat and poisonous evils from the body), but they are different in terms of drug composition and contraindications. 1. Niu Huang Xie Tu Pill is mainly composed of artificial Niu Huang, Gypsum, Rhubarb, Xiong Huang, Platycodonopsis, Scutellaria baicalensis, Ice tablet, Licorice and other drugs. It has the effect of clearing heat and removing toxins (removing heat, toxins and evil qi from the body). It is usually used to treat symptoms such as mouth and tongue sores, swollen and painful gums, sore throat, and swollen and painful eyes. Rash, vomiting, diarrhea and other adverse reactions may occur, and is contraindicated in pregnant and lactating women. Contraindicated in infants and young children. Caution is advised for those with weak spleen and stomach and loose stools. This product contains andrographis and should not be taken in excessive dosage or for a long period of time. This product should not be taken at the same time with other drugs containing andrographis. Caution should be exercised in patients with severe liver damage; caution should be exercised in patients with acute and chronic kidney diseases. 2. Niu Huang Shang Qing Liquid Pill is mainly composed of artificial niu huang, peppermint, chrysanthemum, thorns, dahuric dahurica, Rhizoma Ligustici Chuanxiong, gardenia, rhizoma coptidis and other drugs. It can clear away heat and fire (removing heat and fire from the body), dispersing wind and relieving pain. It is used for headache and dizziness, red eyes and tinnitus, sore throat, mouth and tongue sores, swollen and painful gums, and dry and knotty stools caused by heat and toxicity within the body and wind and fire attacking the body. Avoid smoking, alcohol and spicy food. It is not suitable to take tonic Chinese medicine at the same time during the period of taking the medicine. If the stools increase in frequency and are not formed after taking the medicine, the dosage should be reduced as appropriate. Pregnant women should be cautious. Strictly follow the dosage, this product should not be taken for a long time. Adverse effects have not been clarified. The use of drugs need to be under the guidance of a physician, it is recommended to go to the hospital in a timely manner.