Intraocular pressure (IOP) is the pressure of the contents of the eyeball acting between the wall of the eyeball and the contents. Abnormal intraocular pressure may be due to physiologic and pathologic causes, such as glaucoma and medications. 1. Physiological reasons: When you use your eyes for a long time, your eyes don’t get a good rest, which will make the burden on your eyes bigger, and the intraocular pressure may be affected. In addition, emotional tension, fatigue, etc. can cause abnormal intraocular pressure. 2. Pathologic causes: (1) Glaucoma: common in acute closed angle glaucoma, the discharge channel of atrial fluid is not smooth, the atrial fluid can not be discharged in time, so it causes increased intraocular pressure over time. (2) Drugs: some people have abnormal intraocular pressure, is the use of glucocorticoid hormones or dilating effect of drugs, such as diazepam, tobramycin dexamethasone eye drops, etc., may be due to lead to atrial aqueous humor outflow is impeded, which leads to increased intraocular pressure. When abnormal intraocular pressure occurs, it is recommended to consult a doctor in time, follow the doctor’s instructions for further examination, clarify the cause, and follow the doctor’s instructions for targeted treatment.