Palmoplantar pustules are usually not completely eradicated. Palmoplantar pustules are a specific type of pustular psoriasis, an inflammatory condition associated with the autoimmune system. Common triggers for palmoplantar pustules include smoking, alcohol abuse, drug effects, infections, and stress. Palm and toe pustules are not contagious though and are prone to recurring episodes. It can usually be treated with medication, such as topical creams like mometasone furoate cream and hydrocortisone butyrate cream, and oral medications such as methotrexate and Avitamin A to achieve anti-inflammatory and immunosuppressive effects. Alternatively, optical therapies such as narrow-spectrum medium-wave ultraviolet therapy and photochemotherapy may be used. By avoiding exposure to the triggers of the disease and choosing the appropriate treatment under the guidance of a doctor, patients can avoid recurrent episodes of the disease and even achieve long-term relief of symptoms.