Gliomas that grow to 57 x 38 x 50mm are serious. Whether a glioma is serious or not is often clearly related to the size of the tumor, the location of the growth, and the pathological grading of the tumor. When the glioma grows to 57×38×50mm, due to the large size of the tumor and the rapid growth of the glioma, it often causes obvious edema bands, which leads to obvious compression of the brain tissue, hemiparesis, epilepsy or aphasia of the limbs, and in serious cases, brain hernia may even occur, which may be life-threatening. If the glioma is large in size, occurs in the brainstem, thalamus and other functional areas, and may be closely related to the surrounding blood vessels and nerves, making it even more difficult to completely cut the tumor. This leads to easy recurrence after surgery, so it is said to be more serious. According to the pathological grading of glioma after surgery, although they are all malignant tumors, grade Ⅰ and grade Ⅱ are relatively less malignant and often have better treatment effect and long survival period. On the other hand, grade Ⅲ and Ⅳ are considered to be more malignant and have a shorter survival period. Even if a glioma of 57×38×50mm in size can be completely resected, it will often recur soon and be difficult to treat and endanger the patient’s life. When the glioma grows to 57×38×50mm, it is already more serious. Once found, it is recommended to go to neurosurgery department of a tertiary hospital immediately and undergo surgery and subsequent related treatments as soon as possible.