Slightly coarsened liver parenchymal echogenicity is not necessarily cirrhosis, but may also be viral hepatitis, alcoholic hepatitis, fatty liver and other diseases. Slightly coarsened liver parenchymal echogenicity is a kind of imaging description, by suggesting that the patient’s liver may have damage, but this examination result alone can not confirm the diagnosis of cirrhosis, but need to combine with the characteristics of the medical history, clinical symptoms, auxiliary examination and other information for comprehensive analysis. Cirrhosis is a diffuse proliferation of fibrous tissue in the liver, which may be manifested as weakness, loss of appetite, diarrhea and other symptoms. Slightly thickened echogenicity of liver parenchyma may also be caused by viral hepatitis, alcoholic hepatitis, fatty liver and other diseases. It is recommended to conduct further relevant examinations, such as blood test, urine test, alpha-fetoprotein, CT examination, liver function test, pathological tissue biopsy and other tests for clarification, in order to detect and treat early.