Decline in reproductive function may be caused by endocrine disorders, urinary tract infection, urethritis, weak spermatozoa, etc. It is necessary to choose different treatments according to different causes; the applied drugs usually include mifepristone, ofloxacin, minocycline, hydrocortisone, levofloxacin, erythromycin, etc. 1. Endocrine disorders: patients with endocrine disorders can be treated with mifepristone, hydrocortisone and other medicines under the guidance of doctors; after using them, patients may suffer from pain, headache, fatigue, weakness and other symptoms, and this medicine is prohibited for those who are allergic to this product and other steroid hormones. 2. Urinary tract infection: urinary tract infection can be treated with drugs such as ofloxacin and levofloxacin under the guidance of a doctor, but be aware that patients may experience pain, diarrhea, nausea or vomiting and other symptoms after the use of this drug is contraindicated in patients who have a history of allergy to quinolone antimicrobials. 3. Urethritis: Urethritis can be treated with minocycline, erythromycin and other drugs under the guidance of a doctor, after the use of the patient may experience symptoms such as dizziness, diarrhea, tinnitus, sweating, etc., allergic to tetracycline type of patients with the prohibition of this drug. 4. Weak Sperm: Weak sperm generally refers to normal sperm density, which may be caused by environmental pollution, poor lifestyle, etc. Zinc sulfate, glutathione and other drugs can be used for treatment under the guidance of a doctor, and the patient may experience symptoms such as loss of appetite, nausea, vomiting, etc. after the use of the drug. It is recommended that patients go to the hospital, under the guidance of the doctor’s treatment, and follow the doctor’s instructions for the rational use of drugs.