Hepatitis B teratitis is possible to have a child, generally distinguished into two cases, the first is the patient is not currently pregnant, want to prepare for pregnancy. The other is that the patient with hepatitis B teratitis III is unexpectedly pregnant and how to have a normal delivery without infecting the child. Patients are advised to do hepatitis B virus screening before pregnancy preparation, and if the test result is negative, they can start the pregnancy preparation program. If the test result is positive, it is recommended to take medication such as entecavir, tenofovir, and tibivudine under doctor’s instruction for about half a year, and when the test result turns negative, the pregnancy preparation program can be started after the doctor evaluates the appropriateness. For patients with hepatitis B teratitis III unintended pregnancy, it is also possible to have a normal pregnancy and delivery. However, it is necessary to do mother-to-child interruption in the late stage of pregnancy. Hepatitis B immunoglobulin should be injected within 12 hours after the birth of the child, and the hepatitis B vaccine should be injected at the same time in order to prevent the baby from being infected with hepatitis B. It is recommended that patients with Hepatitis B teratitis should not worry too much, and should seek timely medical advice from their doctors to avoid blindly using medication or making decisions.