The main consideration is breast disease, from the following aspects to consider: first, mastitis, mainly breastfeeding women did not breastfeed in time or did not use the breast pump to suck too much milk out of the body, resulting in a large amount of milk stagnation in the mammary gland or cleaning the nipple is not timely, hygiene is not enough to cause bacterial infection of the breast. Secondly, the estrogen in the body of non-menopausal women changes constantly with the menstrual cycle, and the level of estrogen is higher in the pre-menstrual and menstrual periods, resulting in painful enlargement of the mammary glands. Third, it is considered to be a breast lump or tumor, which needs to be determined as soon as possible through mammography and other tests to determine if it is malignant and to develop a relevant treatment plan so as not to delay the condition.