The enzyme that detoxifies alcohol is called acetaldehyde dehydrogenase in the liver. The active ingredient of alcohol is ethanol, which is absorbed in the stomach and then enters the bloodstream and thus the liver, where it changes from ethanol to acetaldehyde after initial detoxification. As acetaldehyde dehydrogenase is converted to acetic acid, which in turn is converted to water. Therefore, if there is a deficiency of acetaldehyde dehydrogenase, there is a possibility that acetaldehyde will accumulate in the blood and cause flushing, rapid heart rate, sweating, dizziness and headache, and a vasodilating effect. Deficiency of acetaldehyde dehydrogenase may lead to significant damage to liver and kidney function. Therefore, in the case of acetaldehyde dehydrogenase deficiency, it is generally not recommended to drink alcohol as much as possible.