There are several reasons why the whole body is sore after drinking alcohol: 1. After drinking alcohol, the person will rapidly enter three periods, namely the excitement period, the ataxia period and the coma and lethargy period, and is particularly vulnerable to trauma during the ataxia period, usually with traumatic impact, soft tissue contusions, strains, sprains, strains and crush injuries, when the clinical symptoms of whole body soreness will appear. 2. The body will also release inflammatory factors such as leukotrienes, bradykinin, prostacyclin, etc., which will cause skin irritation, body aches and pains and other clinical symptoms.