Stomach cancer is a common malignant tumor, and people are used to the idea that if they have stomach cancer, they have to undergo surgery, and if they cannot undergo surgery, it is “hopeless”. People tend to adopt a negative treatment attitude after the discovery of advanced gastric cancer. Neoadjuvant chemotherapy refers to chemotherapy before gastric cancer surgery to control gastric cancer, expecting to reduce the stage or size of advanced gastric cancer or gastric cancer that is difficult to be removed surgically after chemotherapy, so as to achieve the purpose of surgical removal. The clinical data in recent years support the adoption of neoadjuvant chemotherapy for patients with advanced gastric cancer that cannot be radically resected. The data show that the radical resection rate of advanced gastric cancer patients is significantly increased after neoadjuvant chemotherapy. In my clinical practice, I also found that most patients who were preoperatively evaluated as advanced or difficult to be resected radically had their tumor resection rate greatly improved after neoadjuvant chemotherapy. However, most patients and their family members are afraid of talking about cancer, and once they find out that they have gastric cancer, they will try to have surgery sooner, and once they hear that they have chemotherapy first, they are afraid of delaying surgery, and sometimes they prefer surgery for gastric cancer that is obviously difficult to be resected radically. In the current situation that neoadjuvant chemotherapy is not yet accepted by all doctors and patients, many doctors are also forced to choose surgery for patients with advanced gastric cancer, which leads to a decrease in the resection rate of surgery and insufficient radical resection, and finally affects the treatment effect. Therefore, it is very important to choose the appropriate treatment plan after the diagnosis of gastric cancer. The old habit of preferring surgery should be gradually changed, instead, the resectability rate of gastric cancer should be comprehensively evaluated before selecting the treatment plan according to the stage of gastric cancer. Neoadjuvant chemotherapy should undoubtedly be included as one of the first treatment options. For patients and their families, they should trust the judgment and advice of professional doctors about the disease, rather than choosing treatment options based on their own and previous incomplete knowledge.