Precancerous lesion is a pathological term that refers to certain lesions with obvious risk of cancer, which may turn into cancer if not treated in time. The study of precancerous lesions of gastric cancer is important for the early detection of gastric cancer. It can not only understand the process of gastric cancer and environmental factors from the study of precancerous lesions, but also the follow-up of such lesions can detect early gastric cancer in time. Gastric cancer is one of the common malignant tumors, and its incidence and mortality rate are the first among malignant tumors in China. Like other malignant tumors, the cancer of gastric mucosal epithelial cells is a gradual process, which often goes through years of continuous precancerous stage of gastric cancer, and only a few patients will evolve into gastric cancer. The process of occurrence and development of gastric cancer is as follows: superficial gastritis progresses to atrophic gastritis, then to intestinal epithelial hyperplasia, then to atypical hyperplasia, and finally to gastric cancer. In medical practice, we often encounter patients who come to the doctor with a gastroscopy report with “chronic atrophic gastritis” written on it. They are nervous and afraid that the lesion will become cancerous. So, what is precancerous lesion of gastric cancer? Chronic atrophic gastritis is inaccurate to be concluded by gastroscopy alone through visual observation, but it must be diagnosed by histological examination through biopsy and microscopic observation of chronic inflammation and glandular atrophy in gastric mucosa, and it is still a benign lesion. Since chronic atrophic gastritis is often accompanied by intestinal hyperplasia and atypical hyperplasia of the gastric mucosa, there is a real risk of gastric cancer. Therefore, atrophic gastritis, intestinal epithelial hyperplasia, and atypical hyperplasia are considered as precancerous state of gastric cancer, while chronic atrophic gastritis, gastric ulcer, warty gastritis, gastric polyp, and remnant stomach are often accompanied by the above pathological changes, so they are called precancerous lesions of gastric cancer. Atypical hyperplasia is heterogeneous hyperplasia, which is mainly abnormal proliferation of epithelial and glandular cells and loss of original function, and can be classified into 3 grades: mild, moderate and severe. Intestinal metaplasia comes from proliferating cells in the glandular neck, among which complete small intestinal metaplasia, has a low probability of cancer, while incomplete colonic metaplasia, has a close relationship with the occurrence of intestinal type gastric cancer. Therefore, when the pathological features are: atypical hyperplasia (moderate or severe) or incomplete colonic hyperplasia in the gastric mucosa, the possibility of cancer is obviously increased. Therefore, it is necessary to clarify the diagnosis first. For precancerous lesions of stomach, it is very important to choose the correct treatment plan, which is also an important measure to prevent stomach cancer. In recent years, we have adopted the combination of Chinese and Western medicine in the treatment of precancerous lesions, after protecting mucosa, improving blood circulation of gastric mucosa and increasing regeneration and repair function of gastric mucosal epithelial cells, we found that chronic atrophic gastritis can be transformed into chronic superficial gastritis or restore normal mucosa; the number of intestinal hyperplasia can also be reduced or completely disappeared; mild atypical hyperplasia can be reversed; however, the chances of reversing or disappearing moderate to severe atypical hyperplasia are small. The chance of reversal or disappearance of moderate-to-severe atypical hyperplasia is small. Gastric warty bulges and gastric polyps with atrophy, intestinal epithelial metaplasia or atypical hyperplasia are difficult to reverse. Because 70 to 82% of patients with chronic atrophic gastritis have H. pylori infection, patients should also be treated aggressively for H. pylori infection. Now there is a fourth consensus for the eradication of H. pylori —- Wellspring Consensus, completely abandoned triple therapy, all use quadruple therapy, and according to whether the bacteria are resistant to adjust the treatment plan, and with Chinese medicine to strengthen the spleen and benefit qi, clear heat and detoxification, sterilization effect is better. In summary, combined with my years of clinical experience in combining Chinese and Western medicine, the treatment plan for pre-cancerous gastric lesions is summarized as follows: 1. For simple atrophic gastritis, atrophic gastritis due to bile reflux, intestinal epithelial hyperplasia, or even mild atypical hyperplasia, gastric ulcer combined with intestinal epithelial hyperplasia, mild atypical hyperplasia, etc., we can consider combining Chinese and Western medicine treatment. In life, do not eat pickled products, fried food, smoked food, do not eat leftover food, chew and swallow slowly, insist on drinking two servings of milk every day, drink yogurt if you are bloated, drink fresh milk if you have too much stomach acid, eat more fresh vegetables and fruits, chew and swallow slowly, do not eat too hot food; in medicine, take folic acid, which is the only western medicine that can definitely prevent cancer so far. The drugs that may have prevented cancer are allicin and carotene, which have been negated. Secondly, we should rely on Chinese medicine to treat pre-cancerous lesions in stomach. The concept of Chinese medicine in treating pre-cancerous lesions in stomach is to activate blood circulation and eliminate blood stasis, eliminate swelling and disperse nodules. There are three categories of drugs from weak to strong to activate blood circulation and remove stasis: blood nourishing and blood stasis, such as angelica, rehmannia, etc.; blood activating and removing stasis, such as danshen, safflower, curcuma, etc.; blood activating and removing stasis, such as raw pu huang, perforated nail, etc.; swelling and dispersion drugs, such as dandelion, immortelle, white flowered snake tongue herb, half branch lotus, etc. The reversal rate of precancerous lesions is 40 to 60%. 2.For gastric warty bulge, gastric polyp, macular tumor with precancerous lesions and limited mucosal precancerous lesions (which can be clearly observed under gastroscopy) should be selected for endoscopic treatment, and techniques such as cauterization, extraction, mucosal resection, mucosal peeling can be chosen. Surgical treatment should be considered for extensive lesions or gastric ulcers with moderate atypical hyperplasia.