Sometimes leakage of urine in your sleep in your 30s may be related to physiological factors, heredity, urinary system diseases and other factors. 1. Physiological factors: being too tired during the day, sleeping too much at night, and not waking up easily at night may lead to urine loss. 2. Heredity: urine leakage can also be considered to be related to family genetics, for example, there have been patients in the family with enuresis, which may lead to an increased incidence. 3. Urologic diseases: Diseases of the urinary system, such as urinary malformations and recessive spina bifida, may lead to urinary loss. In addition, the sudden change to a new environment is not adaptable, long-term anxiety may trigger urinary loss. Patients often have the bad habit of holding urine, which may lead to enuresis during night sleep. It is recommended to improve the bad habits, if necessary, go to the hospital urology department to give targeted treatment.