Crohn’s disease of the small intestine can be determined by observing symptoms, colonoscopy and pathological biopsy. 1. Observation of symptoms: Crohn’s disease of the small intestine usually presents with symptoms such as abdominal pain and lumps in the ileocecal region of the abdomen, in which case it can be initially judged that the patient may be suffering from Crohn’s disease of the small intestine. 2. Enteroscopy: Small bowel Crohn’s disease can also be examined by enteroscopy, which can clarify the signs of erosion, ulceration and inflammation in the ileocecal region, and further determine the possible existence of small bowel Crohn’s disease. 3. Pathological biopsy: the lesion tissue needs to be sampled under enteroscopy and sent to the pathology department for laboratory tests, which can usually determine whether it is Crohn’s disease of the small intestine finally. Suspected small bowel Crohn’s disease may appear, it is recommended to go to the regular hospital in time for relevant examinations, to clarify the specific causes in a timely manner, to avoid causing delays in the condition.