What is psoriasis?

  Psoriasis, commonly known as psoriasis, is a common and recurring chronic inflammatory disease. There is a clear seasonality, with most patients experiencing exacerbation in spring and winter and remission in summer. There are approximately 3 million psoriasis patients in China. Since the cause of psoriasis is not fully understood, it may be related to genetic factors, infections, metabolic disorders, and immune dysfunction. Local trauma, irritation, infection, drugs, alcohol consumption, smoking, mental trauma and other internal and external environmental factors can induce or aggravate psoriasis.  Psoriasis lesions are usually found on the trunk and extremities, and are named after the red patches covered with silvery white scales. The most common type of psoriasis is common psoriasis, which can be divided into drip-like, coin-like, map-like and oyster shell-like according to the shape of the lesions, and most patients with psoriasis have these types of lesions. When the hair and thick scales dry and tighten into a bundle, like the head of a hairbrush, it is also called the bundle hair phenomenon; in the oral cavity, the cheek mucosa is more common, and it can also occur in the genital area; in the finger (toe) nail, multiple pinpoint-sized pits appear on the nail plate, like a thimble, called thimble-like nail.  According to the characteristics of the patient’s condition, doctors also divide psoriasis into the common type and the non-common type. The unusual psoriasis includes three more serious types of psoriasis called pustular, arthritic and erythrodermic, all of which are heavier and more complicated to treat than ordinary psoriasis, and often accompanied by other organ diseases. However, the number of incidences is small, accounting for only about 5% of common psoriasis.  The causes of psoriasis are complex and not yet fully understood, so there is no treatment method that can prevent the disease from occurring in advance or cure it and never recur. At present, there are many safe and effective clinical treatments for different types of psoriasis of different degrees, so that the condition can be relieved and the quality of life of psoriasis patients can be improved.  The first of the drug treatments is retinoic acid, such as avobenzone, which is suitable for all types of psoriasis. It is considered a product of the advances in dermatological treatment in the 1980s. Immunosuppressive agents are mainly indicated for the more severe non-common psoriasis. Antibiotics should be used in the presence of significant infection. The use of topical medications is very common and does provide ease of administration, rapid efficacy and few side effects. However, patients who have been using topical hormonal medications for a long time still need to have a doctor evaluate the safety of the medication. Side effects include thinning of the skin, dilated capillaries, subcutaneous bleeding and resistance to the hormone. In addition, physical therapy, such as ultraviolet light therapy, medicinal bath therapy, mineral bath therapy, etc., are safer and more effective treatments.