Cranial trauma is one of the more common injuries in life, and most of them may result in skull defects. So repairing craniocerebral trauma surgery inevitably involves cranial repair. Cranial repair is now a relatively routine procedure in neurosurgery, and the technique is relatively mature. After the skull defect, timely cranial bone repair is very necessary. This is because patients with cranial defects often have a heavy burden of thought such as insecurity, and can cause headaches, dizziness, fear of vibration and other syndromes. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. Therefore, in order to restore the airtightness of the cranial cavity, keep the physiological intracranial pressure stable, and alleviate the syndrome of cranial defect, patients with cranial defects should undergo cranial repair surgery in time. In cranial bone repair surgery, the repair material is an important factor affecting the repair effect. At present, the commonly used cranial bone repair material is titanium mesh material, but this traditional metal material is not very ideal, and there are also poor thermal insulation, poor histocompatibility, easy to produce rejection, interference with nuclear magnetic CT examination and other drawbacks. A more advanced repair material, polyether ether ketone PEEK, has emerged. Our team is using this material extensively and has achieved good clinical results. This PEEK material is much better than the traditional titanium mesh, and it has excellent performance in strength, elasticity, thermal insulation, histocompatibility, and radiation transmittance, making it a new trend in cranial bone repair materials.