Gastric perforation patients can not smoke, because most of the gastric perforation is caused by peptic ulcer, in the treatment of peptic ulcer, smoking is harmful to the healing of the ulcer. Because the toxic substances in the cigarette can reduce the blood supply to the surface of the gastric mucosa, the reduction of blood supply to the surface of the gastric mucosa will affect the healing of the ulcer. The healing of ulcers requires a lot of nutrients to provide energy to promote its healing, protective factors increase when the ulcer can heal faster. Smoking reduces the blood supply to the surface of the gastric mucosa, and this inadequate blood supply to the ulcer site will affect the healing of the ulcer. Therefore, patients with gastric perforation should try not to smoke, and increase the protective factors of the gastric mucosa to improve the healing rate of the ulcer.