Bilateral lacunar cerebral infarction can be treated with oral aspirin antiplatelet coagulation. Oral statins are used to regulate lipids and stabilize plaque, and simvastatin tablets, resuvastatin calcium tablets and atorvastatin calcium tablets are applied clinically. If triglyceride is greater than 2.1mmol/L, we can consider applying beta-lipid-lowering drugs for lipid-lowering treatment. At the same time, drugs to activate blood circulation and improve blood stasis should be applied, commonly used ones are Shu Xuning, Vibramycin Lutong and Chuanxiong Xiong Zhen. Neuroprotective therapy was also given with the application of olaxetan capsules, piracetam tablets, cytarabine sodium capsules, vincristine tablets and cerebroside myosin. Most of the patients have a history of hyperlipidemia, diabetes mellitus and hypertension, and should be actively given to regulate blood pressure-lowering drugs, which can be used in long-acting preparations, commonly used amlodipine and irbesartan. Metformin is preferred for hypoglycemic drugs and statins should be applied for lipid regulation.