Hormone refers to glucocorticoids, long-term use of glucocorticoids on the human body has the following hazards: First, elevated blood sugar, glucocorticoids have the effect of elevating blood sugar, long-term use of glucocorticoids will have abnormal glucose tolerance, and even the formation of steroid diabetes. Second, hypertension, glucocorticoids have the role of sodium and potassium, long-term use of glucocorticoids will cause the body to increase blood pressure. Third, peptic ulcer, long-term use of glucocorticosteroids is easy to stimulate gastric acid secretion, the formation of gastric and duodenal peptic ulcer. Fourth, osteoporosis, long-term use of glucocorticoids will affect calcium absorption and calcium deposition in the bones, resulting in osteoporosis. Fifth, long-term use of glucocorticoids may cause mental excitement, irritability, and even mental abnormality. Sixth, other aspects, long-term use of glucocorticoids will lead to full-moon face, buffalo back, centripetal obesity and other body shape changes.