Adverse effects such as constipation, nausea, allergies, liver and kidney damage are seen with quadruple therapy; the adverse effects disappear after stopping the drug, and there is no such thing as a few years of recovery. Quadruple therapy is a treatment for Helicobacter pylori infection, and its treatment plan is two antibiotic drugs, a proton pump inhibitor, and a bismuth agent, such as bismuth potassium citrate + omeprazole + metronidazole or tinidazole, clarithromycin, amoxicillin, levofloxacin, and other two of the antibiotics, and the course of treatment is usually 10-14 days. Common adverse reactions: bitter mouth, dry mouth, loss of appetite, diarrhea, constipation, drug allergy and mild liver and kidney injury. Although quadruple therapy can cause a variety of adverse reactions, but most of the symptoms are mild, or no adverse reactions, no need to be overly nervous, generally in a few days after stopping the drug its discomfort can gradually reduce the symptoms and gradually return to normal, and does not require several years of time for recovery. To summarize, the application of quadruple therapy in the clinic has been more mature, the adverse reactions caused by it are controllable, generally will not cause great harm to the body, no need to be particularly nervous, but must be carried out under the guidance of a professional physician, the emergence of uncomfortable symptoms, you need to consult a professional physician’s diagnosis and treatment recommendations in a timely manner.