Digoxin is an orally administered digitalis-like positive inotropic drug that is often used clinically in the anti-heart failure treatment of patients with chronic heart failure. Because digoxin is prone to toxicity, if digoxin is needed, it is usually given in small doses for long-term maintenance and should not be given in excessive doses. Smaller doses should be given especially to elderly patients over 70 years of age, as well as to patients with renal impairment or low body weight. It is important to be alert to the development of digitalis toxicity during use, especially in the presence of myocardial ischemia and hypoxia, as well as hypokalemia, hypomagnesemia, hypothyroidism, and renal insufficiency, which should be closely observed. Discontinue the drug as soon as the patient develops cardiac arrhythmia, as well as symptoms of gastrointestinal tract, yellow-green vision and other symptoms of digoxin toxicity. For patients with outflow tract obstruction, such as hypertrophic cardiomyopathy, aortic stenosis, and severe bradycardia, digoxin should be contraindicated.