The fibrinolytic system is the most important anticoagulation system in the body. During lysis, thrombin hydrolyzes fibrin, releasing soluble fibrin monomers, which, under the action of factor xIIIa, form stable cross-linked fibrin. In late stages of disseminated intravascular coagulation, the fibrinolytic system is activated due to intravascular coagulation, resulting in secondary fibrinolysis and more pronounced bleeding symptoms. What are the preventive methods for secondary fibrinolysis enhancement? 1. Prevention and control of primary diseases. Prevention and removal of the cause of DIC is the fundamental measure to prevent and treat DIC, such as control of infection, removal of stillbirth or retained placenta, etc. For some mild DIC, as long as the cause is removed in time, the condition can recover rapidly. 2.Improve microcirculatory disorders. Adopt measures such as expanding blood volume and relieving vasospasm to unblock the blocked microcirculation as early as possible. 3.Establish a new dynamic balance between coagulation and fibrinolysis. In the hypercoagulable period, anticoagulant drugs such as heparin, low molecular dextran, aspirin, etc. can be applied to prevent the initiation and progress of the coagulation process and the formation of new thrombi. In patients with very serious bleeding tendency, blood transfusion or supplementation of platelets and other coagulation substances as well as the use of fibrinolytic inhibitors can be used. 4, the diet should pay attention to light, more vegetables porridge, noodle soup and other easily digested and absorbed food is better. 5.Eat more fresh fruits and vegetables to ensure the intake of vitamins. 6.Give liquid or semi-liquid food, such as various kinds of porridge, rice soup, etc. Supplementation of platelets and clotting factors when transfused with blood or given fibrinogen before heparin can provide the substrate for clotting for microthrombosis and promote the development of DIC. However, the application of heparin can aggravate bleeding if the coagulation factor is too low. Blood should be transfused (preferably fresh blood) or supplemented with fibrinogen, the latter raising plasma fibrinogen by 25 mg/dl per gram of preparation, with hemostatic effect only when fibrinogen concentration exceeds 100 mg/dl.