Since food in the stomach has little effect on the absorption of amoxicillin after taking it, it can be taken orally before or after meals, and the specific medication should be administered under a doctor’s supervision. Amoxicillin is a broad-spectrum antibiotic of the penicillin class. The commonly used dosage forms are tablets, capsules, granules and chewable tablets. It can be used to treat upper and lower respiratory tract infections, genitourinary tract infections and acute simple gonorrhea. Combined use with clarithromycin, lansoprazole, and bismuth potassium citrate can eradicate Helicobacter pylori. Since amoxicillin is less irritating to the gastrointestinal tract and the presence or absence of food in the stomach has little effect on the absorption of amoxicillin, it can be taken orally before or after meals. Gastrointestinal reactions such as nausea, vomiting, diarrhea, and pseudomembranous enteritis, as well as allergic reactions such as rash, drug fever, and asthma, may occur in some patients after taking the drug. Penicillin allergy and positive penicillin skin tests are contraindicated. Amoxicillin must be taken under the guidance of a doctor on medical advice, not blindly used on their own.