The middle stage of hepatitis B virus infection is when hepatitis B develops. Hepatitis B is a contagious disease caused by hepatitis B virus infection, most people infected with hepatitis B just become hepatitis B virus carriers, and this situation usually does not need treatment. However, if you are infected with hepatitis B and develop hepatitis B virus, then this is the middle stage of hepatitis B virus infection, you need to be treated by antiviral treatment, antiviral treatment can choose interferon or oral nucleoside antiviral drugs. In the middle stage of hepatitis B, the virus is still infectious in the body. Most people in the middle stage of hepatitis B suffer from weight loss, liver pain, or lack of concentration, which affects their normal life. Active antiviral treatment is needed to protect the liver. If not treated in time, it may still lead to cirrhosis and liver cancer. Hepatitis B patients are advised to seek timely medical treatment to avoid delaying their condition, and usually need to pay attention to rest, do not drink, do not stay up late.