Consumption of Si-Xing Pills may result in dark stools, which will usually return to normal after stopping the medicine. However, dark stool may also be caused by physiological and pathological factors, and the cause should be clarified and treated symptomatically. Four Elimination Pills is composed of rhubarb, petunia seeds, aromatic herbs, betel nut, five lingzhi, etc. It has the efficacy of eliminating water, phlegm, food, stagnation of qi, guiding stagnation and laxative effect, and can be used for treating qi, food, phlegm, water, stagnation of stagnation and unresolved stagnation, fullness of the chest and epigastrium, abdominal distension and pain, and constipation of the bowels. Taking certain Chinese medicine ingredients may lead to black stool, usually after stopping the drug will return to normal, the body without other discomforts. Physiological factors: when the patient consumes animal blood such as pig’s blood, chicken blood, etc., or consumes dragon fruit, etc., can lead to black stools, usually without treatment, stop eating two to three days after the return to normal, and will not lead to physical discomfort. Pathological factors: such as upper gastrointestinal hemorrhage, bleeding greater than 50ml, or digestive tract tumors, polyps, etc., can lead to bleeding, there will be black stool, this time should be clear cause of the symptomatic treatment. Four elimination pills should be used under the guidance of a doctor, the body is weak, the spleen is deficient in feces, there are people with external sensations and pregnant women should not be taken. When there is a black stool, excluding drugs and physiological factors, should go to the hospital in a timely manner, to clarify the cause of the symptomatic treatment, so as to avoid delaying the condition.