Closed-cell pimples, or acne, are not recommended to be squeezed, as they may lead to bacterial infections. Acne, especially in the facial triangle, may lead to meningitis and brain abscesses if infection occurs. If the symptoms are severe, it is recommended to go to the hospital and use medication under a doctor’s supervision. Acne is not recommended for patients to squeeze themselves. This is because the operation process can easily lead to bacterial infection, and after bacterial infection, abscesses may appear and aggravate the symptoms. Especially for acne in the facial triangle, if the operation is not done properly and causes infection, it may also cause central nervous system infections such as meningitis and brain abscess. Therefore, it is not recommended for patients to operate on their own. If acne is severe, medications such as retinoid ointment, azelaic acid and benzoyl peroxide can be applied to the affected area. If you need to use drugs, you need to use under the guidance of a doctor, do not use drugs without authorization.