Inflammation of the tibial tubercle often manifests itself as a significant tingling in the tibial tuberosity, which is noticeably painful when pressed. The tibial tuberosity is a location where the patellar ligament attaches, and regular pulling of the ligament can lead to aseptic inflammation. This sterile inflammation is usually characterized by stabbing pain, which is aggravated by weight-bearing, flexion and extension of the knee joint. On plain radiographs of the knee, there are often no obvious signs of abnormality because of the inflammatory response, and in severe cases there may be increased translucency and calcification of the patellar ligament on plain radiographs. Inflammation of the tibial tuberosity should be treated with reduced weight-bearing, reduced activity, and nonsteroidal anti-inflammatory drugs, and the prognosis is good in most cases.