Some patients will apply creams due to the treatment of certain diseases. If the joints are painful, they may apply rheumatism pain relief cream, musk strong bone cream, etc. After applying the creams, local burning, itching or pain may occur. When these symptoms appear, it suggests that the patient is allergic to the ointment, such as drugs, adhesives, local impermeability, irritation, etc. Local contact dermatitis, the patient must immediately stop using, or remove the ointment, and should be treated actively according to contact dermatitis, allergic dermatitis. Ointment is a kind of topical drug, the topical drug is attached to some kind of dressing, using the adhesive effect on the skin, to achieve the treatment of some kind of skin disease, or some kind of joint pain. Patients who experience adverse clinical symptoms while applying the cream in their daily life need to stop using the cream immediately.