Methylprednisolone and Prednisone Acetate Differences

The distinction between methylprednisolone and prednisone acetate can be made in terms of the way the drug is administered, the effectiveness of the drug, and the side effects.
1. Mode of administration: Methylprednisolone is highly water-soluble and has a long-lasting effect, and is mostly made into injectable needles, while the water-solubility of prednisone acetate is poorer, and it is mostly taken orally.
2. Drug effect: generally speaking, prednisone acetate is more commonly used, it is a kind of mild hormone, while methylprednisolone is a kind of more potent hormone, but the side effects are also greater.
3.Side effects.
(1) Liver function: Prednisone needs to go through liver activation, which may cause some burden on the liver, so it is not recommended to use it for abnormal liver function, while Methylprednisolone is basically not a burden on the liver.
(2) Sodium retention: Methylprednisolone has no effect on the water and salt metabolism of the body, while prednisone exists a certain effect, so when there is sodium retention and edema, methylprednisolone preparations should be chosen.
It is worth noting that both methylprednisolone and prednisone are hormone drugs, both of which will have certain side effects on the organism, and the selection of drug dosage and type must be carried out under the guidance of doctors. At the same time, you can not increase or decrease the dose or stop the drug on your own.