The phenomenon of coughing yellow sputum and yellow runny nose is a cold caused by bacterial infection, and from the perspective of Western medicine, antibiotics can be used for anti-inflammatory treatment. If there is no allergy to penicillin, you can take amoxicillin or amoxicillin clavulanate potassium orally; if there is no allergy to cephalosporins, you can also use cefaclor or cefadroxil for anti-inflammatory treatment. If from the perspective of Chinese medicine, it is the occurrence of wind-heat cold, wind-heat cold will appear coughing yellow sputum, yellow nasal discharge, easily accompanied by severe sore throat and fever, need to use clear heat and detoxification of Chinese medicine for relief. You can use Pu Di Lan Anti-inflammatory Oral Liquid or Lung Power Cough Compound, which have good effect of clearing heat, detoxification and anti-inflammation, especially Lung Power Cough Compound, which has the effect of relieving cough, resolving phlegm and moistening the lung, and has a better effect on coughing up yellow phlegm, and these drugs should be taken three times a day.