When you wake up in the morning with a sore throat and yellow sputum, first of all, there must be inflammation in the throat, so there will be congestion and edema, and there will be local redness, swelling, heat and pain, so you will feel a sore throat. The causes of yellow sputum are complicated. First of all, septicemia in the throat may also lead to yellow sputum. If the infection in the upper respiratory tract is extended to the lower respiratory tract, it may also cause yellow sputum. If there is an infection in the bronchial tubes and lungs, yellow sputum will also be discharged, so that there will be yellow sputum. For upper respiratory tract infections, oral antibiotics can be given for treatment, such as oral cefixime or cefradine. For infections of the lower respiratory tract, the effect of oral medication is often insufficient and intravenous drip antibiotics are needed for treatment. Clinically, if there is no allergy to cephalosporin, intravenous ceftriaxone can be administered intravenously for treatment.