Left adrenal thickening may cause high blood pressure. Adrenal gland thickening may be seen in primary aldosteronism, pheochromocytoma, and cortisolism. When adrenal gland thickening is found to exist or accompanied by adrenal adenoma, there may be an increase in hormones such as aldosterone, and clinical symptoms such as hypertension and hypokalemia are often indicative of the presence of primary aldosteronism, suggesting the possibility of secondary hypertension. Clinical symptoms such as paroxysmal headache, pallor, persistent increase in blood pressure, and paroxysmal exacerbation need to be excluded from the presence of pheochromocytoma. Adrenal cortical hyperplasia is also seen on CT examination of the adrenal glands in the case of cortisolism, which is often manifested clinically as centripetal obesity, hypertension, elevated blood glucose, osteoporosis, and so on. When adrenal hyperplasia is found, it is recommended to consult the endocrinology department of regular hospitals for standardized treatment.