A high level of anti-histone antibody suggests that the patient may have autoimmune diseases, such as drug-induced lupus and systemic lupus erythematosus, and the specific cause should be clarified under the guidance of a doctor.
Anti-histone antibody is one kind of autoantibody, histone is the main protein that makes up chromatin, and normal people are usually negative for this antibody. A high level of anti-histone antibodies suggests a possible combination with drug-induced lupus, which is important for diagnosis and differentiation. In addition, a variety of connective tissue diseases, such as systemic lupus erythematosus, may also present with elevated anti-histone antibodies, but they are not diagnostic.
Patients with high anti-histone antibodies are advised to go to the rheumatology and immunology department of the hospital for diagnosis and treatment under the guidance of the doctor.