Pimples are usually acne, and the creams commonly used to treat acne include retinoic acid cream, adapalene gel, and fusidic acid cream. 1. Vitamin A Acid Cream: It is mainly used for common acne and follicular keratosis. It treats acne by dissolving keratin and regulating the growth and keratinization of epithelial cells. Common adverse reactions include skin irritation such as erythema flaking and burning. It is contraindicated in pregnant women, contraindicated during breastfeeding, contraindicated in those who are allergic to the drug, and contraindicated in the eyes. 2. Adapalene Gel: used for papules and pustules as the main manifestation of common acne. It has the effect of regulating the differentiation of follicular epithelial cells and promoting keratolysis, thus it can treat acne. Common adverse reactions are skin irritation causing erythema, dryness and itching. It is prohibited for those who are allergic to the drug. 3. Fusidic acid cream: it is an antibiotic drug, which can be used for skin infections caused by gram-positive cocci, and can be used for the adjuvant treatment of acne vulgaris. Topical application of this product is generally no side effects, occasionally there will be a slight sense of irritation, pregnant and lactating women should be used with caution. All drugs should be used under the guidance of a professional doctor, and should not be abused blindly by yourself.