Pain in the middle of the chest may be related to muscle strain, cardiogenic pain, pleural lesions, esophageal disease, costochondritis, etc. 1. Muscle strain: Strenuous exercise may cause pectoral muscle strain, which may manifest as pain in the middle of the chest, and may be accompanied by local muscle soreness and discomfort. 2. Cardiogenic pain: cardiogenic pain caused by angina pectoris and myocardial infarction is mainly manifested as pain in the middle of the chest, which is mostly seen in middle-aged and old-aged patients, mostly accompanied by dyspnea, and the nature of the pain is generally more severe, with high risk of the condition and possible sudden death. 3. Pleural lesions: pleural lesions, such as pleurisy, can be caused by a variety of reasons, because of fibrous hyperplasia between the dirty pleura and the wall pleura, friction between each other, when coughing or deep breathing may cause pain in the chest, the symptom may be alleviated after appropriate rest. 4. Esophageal diseases: such as esophagitis, gastroesophageal reflux disease, etc., due to the reflux of gastric acid and other gastric contents to stimulate the esophageal mucosa, which is manifested as pain in the middle of the forehead. 5. Costochondritis: mostly caused by non-infectious factors, chest pain and pressure pain, which can be manifested as pain in the middle of the chest, and redness, swelling, heat and pain of local skin caused by infectious factors. The pain may radiate to the back of the shoulders, armpits, neck and chest, and may be aggravated by deep breathing, activity or exertion. It is suggested that there are many reasons for the symptoms of pain in the middle of the chest, it is recommended to go to the hospital in time for examination, to identify the causes and then under the guidance of the doctor treatment.